Centro Andaluz de Biología Molecular y Medicina Regenerativa

Publications

/Publications
Selected publications in 2023:

  1. van Dinther M, Cunningham KT, Singh SP, White MPJ, Campion T, Ciancia C, van Veelen PA, de Ru AH, González-Prieto R, Mukundan A, Byeon CH, Staggers SR, Hinck CS, Hinck AP, Dijke PT, Maizels RM. 2023. CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-? mimic. Proc Natl Acad Sci U S A. 120(34):e2302370120.

  2. van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, Schärer OD, Luijsterburg MS. 2023. A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair. Proc Natl Acad Sci U S A. 120(11):e2208860120.

  3. Harris RJ, Heer M, Levasseur MD, Cartwright TN, Weston B, Mitchell JL, Coxhead JM, Gaughan L, Prendergast L, Rico D, Higgins JMG. 2023. Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation. Nat Commun. 14(1):7243.

  4. Rivadulla C, Pardo-Vazquez JL, de Labra C, Aguilar J, Suarez E, Paz C, Álvarez-Dolado M, Cudeiro J. 2023. Transcranial static magnetic stimulation reduces seizures in a mouse model of Dravet syndrome. Exp Neurol. 370:114581.

  5. de Paz JL, García-Jiménez MJ, Jafari V, García-Domínguez M, Nieto PM. 2023. Synthesis and interaction with growth factors of sulfated oligosaccharides containing an anomeric fluorinated tail. Bioorg Chem. 141:106929.

  6. Bayona-Feliu A, Herrera-Moyano E, Badra-Fajardo N, Galván-Femenía I, Soler-Oliva ME, Aguilera A. 2023. The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts. Nat Commun. 14(1):6890.

  7. El Yousfi Y, Mora-Molina R, López-Rivas A, Yerbes R. 2023. Role of the YAP/TAZ-TEAD Transcriptional Complex in the Metabolic Control of TRAIL Sensitivity by the Mevalonate Pathway in Cancer Cells. Cells. 12(19):2370.

  8. Gómez-González B, Aguilera A. 2023. Break-induced RNA-DNA hybrids (BIRDHs) in homologous recombination: friend or foe?. EMBO Rep. Online ahead of print.

  9. Camino LP, Dutta A, Barroso S, Pérez-Calero C, Katz JN, García-Rubio M, Sung P, Gómez-González B, Aguilera A. 2023. DICER ribonuclease removes harmful R-loops. Mol Cell. Online ahead of print.

  10. Andrés-San Román JA, Gordillo-Vázquez C, Franco-Barranco D, Morato L, Fernández-Espartero CH, Baonza G, Tagua A, Vicente-Munuera P, Palacios AM, Gavilán MP, Martín-Belmonte F, Annese V, Gómez-Gálvez P, Arganda-Carreras I, Escudero LM. 2023. CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia. Cell Rep Methods. Online ahead of print.

  11. Martín F, Blanco-Suárez M, Zambrano P, Cáceres O, Almirall M, Alegre-Martín J, Lobo B, González-Castro AM, Santos J, Domingo JC, Jurek J, Castro-Marrero J. 2023. Increased gut permeability and bacterial translocation are associated with fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome: implications for disease-related biomarker discovery. Front Immunol. 14:1253121.

  12. González-Arzola K, Díaz-Quintana A. 2023. Mitochondrial Factors in the Cell Nucleus. Int J Mol Sci. 24(17):13656.

  13. Martín-Vázquez E, Cobo-Vuilleumier N, López-Noriega L, Lorenzo PI, Gauthier BR. 2023. The PTGS2/COX2-PGE2 signaling cascade in inflammation: Pro or anti? A case study with type 1 diabetes mellitus. Int J Biol Sci. 19(13):4157-4165.

  14. Rodríguez-Real G, Domínguez-Calvo A, Prados-Carvajal R, Bayona-Feliú A, Gomes-Pereira S, Balestra FR, Huertas P. 2023. Centriolar subdistal appendages promote double-strand break repair through homologous recombination. EMBO Rep. Online ahead of print.

  15. García-Vílchez R, Añazco-Guenkova AM, López J, Dietmann S, Tomé M, Jimeno S, Azkargorta M, Elortza F, Bárcena L, Gonzalez-Lopez M, Aransay AM, Sánchez-Martín MA, Huertas P, Durán RV, Blanco S. 2023. N7-methylguanosine methylation of tRNAs regulates survival to stress in cancer. Oncogene. Online ahead of print.

  16. Lluch A, Latorre J, Serena-Maione A, Espadas I, Caballano-Infantes E, Moreno-Navarrete JM, Oliveras-Cañellas N, Ricart W, Malagón MM, Martin-Montalvo A, Birchmeier W, Szymanski W, Graumann J, Gómez-Serrano M, Sommariva E, Fernández-Real JM, Ortega FJ. 2023. Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence. Nat Commun. 14(1):5106.

  17. de Oya IG, Manzano-López J, Álvarez-Llamas A, Vázquez-Aroca MP, Cepeda-García C, Monje-Casas F. 2023. Characterization of a novel interaction of the Nup159 nucleoporin with asymmetrically localized spindle pole body proteins and its link with autophagy. PLoS Biol. 21(8):e3002224.

  18. Salas-Lloret D, Jansen NS, Nagamalleswari E, van der Meulen C, Gracheva E, de Ru AH, Otte HAM, van Veelen PA, Pichler A, Goedhart J, Vertegaal ACO, González-Prieto R. 2023. SUMO-activated target traps (SATTs) enable the identification of a comprehensive E3-specific SUMO proteome. Sci Adv. 9(31):eadh2073.

  19. Berná G, López-Bermudo L, Escudero-López B, Martín F. 2023. We are what we eat: The role of lipids in metabolic diseases. Adv Food Nutr Res. 105:173-219.

  20. Samra N, Jansen NS, Morani I, Kakun RR, Zaid R, Paperna T, Garcia-Dominguez M, Viner Y, Frankenthal H, Shinwell ES, Portnov I, Bakry D, Shalata A, Shapira Rootman M, Kidron D, Claessens LA, Wevers RA, Mandel H, Vertegaal ACO, Weiss K. 2023. Exome sequencing links the SUMO protease SENP7 with fatal arthrogryposis multiplex congenita, early respiratory failure and neutropenia. J Med Genet. Online ahead of print.

  21. Barrientos-Moreno M, Maya-Miles D, Murillo-Pineda M, Fontalva S, Pérez-Alegre M, Andujar E, Prado F. 2023. Transcription and FACT facilitate the restoration of replication-coupled chromatin assembly defects. Sci Rep. 13(1):11397.

  22. Pérez-Cabello JA, Silvera-Carrasco L, Franco JM, Capilla-González V, Armaos A, Gómez-Lima M, García-García R, Yap XW, Leal-Lasarte M, Lall D, Baloh RH, Martínez S, Miyata Y, Tartaglia GG, Sawarkar R, García-Domínguez M, Pozo D, Roodveldt C. 2023. MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS. PNAS. 120(28):e2302143120.

  23. Fan C, González-Prieto R, Kuipers TB, Vertegaal ACO, van Veelen PA, Mei H, Ten Dijke P. 2023. The lncRNA LETS1 promotes TGF-?-induced EMT and cancer cell migration by transcriptionally activating a T?R1-stabilizing mechanism. Sci Signal. 16(790):eadf1947.

  24. Iglesias-Ortega L, Megías-Fernández C, Domínguez-Giménez P, Jimeno-González S, Rivero S. 2023. Cell consequences of loss of function of the epigenetic factor EHMT1. Cell Signal. 108:110734.

  25. Comaills V, Castellano-Pozo M. 2023. Chromosomal Instability in Genome Evolution: From Cancer to Macroevolution. Biology (Basel). 12(5):671.

  26. Carrillo-Carrión C, Comaills V, Visiga AM, Gauthier BR, Khiar N. 2023. Enzyme-Responsive Zr-Based Metal-Organic Frameworks for Controlled Drug Delivery: Taking Advantage of Clickable PEG-Phosphate Ligands. ACS-Appl Mater. 15(23):27600-27611.

  27. Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, Bakal C, Shackley F, Aguilera A, Stewart GS, Vyas YM, Niedzwiedz W. 2023. Actin nucleators safeguard replication forks by limiting nascent strand degradation. Nucleic Acids Res. 51(12):6337-6354.

  28. Salazar-Bermeo J, Moreno-Chamba B, Martínez-Madrid MC, Valero M, Rodrigo-García J, Hosseinian F, Martín-Bermudo F, Aguado M, de la Torre R, Martí N, Saura D. 2023. Preventing Mislabeling: A Comparative Chromatographic Analysis for Classifying Medical and Industrial Cannabis. Molecules. 28(8):3552.

  29. Aguilera P, López-Contreras AJ. 2023. ATRX, a guardian of chromatin. Trends Genet. 39(6):505-519.

  30. Gönczy P, Balestra FR. 2023. Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos. Genetics. 224(1):iyad048.

  31. Aguilera P, Dubarry M, Géli V, Simon MN. 2023. NPCs and APBs: two HUBs of non-canonical homology-based recombination at telomeres?. Cell Cycle. 22(10):1163-1168.

  32. Goikoetxea-Usandizaga N, Bravo M, Egia-Mendikute L, Abecia L, Serrano-Maciá M, Urdinguio RG, Clos-García M, Rodríguez-Agudo R, Araujo-Legido R, López-Bermudo L, Delgado TC, Lachiondo-Ortega S, González-Recio I, Gil-Pitarch C, Peña-Cearra A, Simón J, Benedé-Ubieto R, Ariño S, Herranz JM, Azkargorta M, Salazar-Bermeo J, Martí N, Varela-Rey M, Falcón-Pérez JM, Lorenzo Ó, Nogueiras R, Elortza F, Nevzorova YA, Cubero FJ, Saura D, Martínez-Cruz LA, Sabio G, Palazón A, Sancho-Bru P, Elguezabal N, Fraga MF, Ávila MA, Bataller R, Marín JJG, Martín F, Martínez-Chantar MLv. 2023. The outcome of boosting mitochondrial activity in alcoholic liver disease (ALD) is organ-dependent. Hepatology. 78(3):878-895.

  33. Panneman DM, Hitti-Malin RJ, Holtes LK, de Bruijn SE, Reurink J, Boonen EGM, Khan MI, Ali M, Andréasson S, De Baere E, Banfi S, Bauwens M, Ben-Yosef T, Bocquet B, De Bruyne M, de la Cerda B, Coppieters F, Farinelli P, Guignard T, Inglehearn CF, Karali M, Kjellström U, Koenekoop R, de Koning B, Leroy BP, McKibbin M, Meunier I, Nikopoulos K, Nishiguchi KM, Poulter JA, Rivolta C, Rodríguez de la Rúa E, Saunders P, Simonelli F, Tatour Y, Testa F, Thiadens AAHJ, Toomes C, Tracewska AM, Tran HV, Ushida H, Vaclavik V, Verhoeven VJM, van de Vorst M, Gilissen C, Hoischen A, Cremers FPM, Roosing S. 2023. Cost-effective sequence analysis of 113 genes in 1,192 probands with retinitis pigmentosa and Leber congenital amaurosis. Front Cell Dev Biol. 11:1112270.

  34. Baliña-Sánchez C, Aguilera Y, Adán N, Sierra-Párraga JM, Olmedo-Moreno L, Panadero-Morón C, Cabello-Laureano R, Márquez-Vega C, Martín-Montalvo A, Capilla-González V. 2023. Generation of mesenchymal stromal cells from urine-derived iPSCs of pediatric brain tumor patients. Front Immunol. 14:1022676.

  35. Caballano-Infantes E, Ho-Plágaro A, López-Gómez C, Martín-Reyes F, Rodríguez-Pacheco F, Taminiau B, Daube G, Garrido-Sánchez L, Alcaín-Martínez G, Andrade RJ, García-Cortés M, Lucena MI, García-Fuentes E, Rodríguez-Díaz C. 2023. Membrane Vesicles of Toxigenic Clostridioides difficile Affect the Metabolism of Liver HepG2 Cells. Antioxidants (Basel). 12(4):818.

  36. Yalçin Z, Koot D, Bezstarosti K, Salas-Lloret D, Bleijerveld OB, Boersma V, Falcone M, González-Prieto R, Altelaar M, Demmers JAA, Jacobs JJL. 2023. Ubiquitinome profiling reveals in vivo UBE2D3 targets and implicates UBE2D3 in protein quality control. Mol Cell Proteomics. 22(6):100548.

  37. Williams JD, Zhu D, García-Rubio M, Shaltz S, Aguilera A, Jinks-Robertson S. 2023. Spontaneous deamination of cytosine to uracil is biased to the non-transcribed DNA strand in yeast. DNA Repair (Amst) . 126:103489.

  38. Moshtaghion SM, Abolhosseini M, Yaseri M, Hosseini SB, Kanavi MR. 2023. Diagnostic accuracy of confocal scan in detecting acanthamoeba keratitis and fungal keratitis: a systematic review and meta-analysis. Int Ophthalmol. 43(8):3011-3022.

  39. Sola-García A, Cáliz-Molina MÁ, Espadas I, Petr M, Panadero-Morón C, González-Morán D, Martín-Vázquez ME, Narbona-Pérez ÁJ, López-Noriega L, Martínez-Corrales G, López-Fernández-Sobrino R, Carmona-Marin LM, Martínez-Force E, Yanes O, Vinaixa M, López-López D, Reyes JC, Dopazo J, Martín F, Gauthier BR, Scheibye-Knudsen M, Capilla-González V, Martín-Montalvo A. 2023. Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging. Commun Biol. 6(1):250.

  40. López-Terrones E, Paz V, Campa L, Conde-Berriozabal S, Masana M, Artigas F, Riga MS. 2023. Differential Modulation of Dorsal Raphe Serotonergic Activity in Rat Brain by the Infralimbic and Prelimbic Cortices. Int J Mol Sci. 24(5):4891.

  41. Lachaud CC, Cobo-Vuilleumier N, Fuente-Martin E, Diaz I, Andreu E, Cahuana GM, Tejedo JR, Hmadcha A, Gauthier BR, Soria B. 2023. Umbilical cord mesenchymal stromal cells transplantation delays the onset of hyperglycemia in the RIP-B71 mouse model of experimental autoimmune diabetes through multiple immunosuppressive and anti-inflammatory responses. Front Cell Dev Biol. 11:1089817.

  42. Marchena-Cruz E, Camino LP, Bhandari J, Silva S, Marqueta-Gracia JJ, Amdeen SA, Guillén-Mendoza C, García-Rubio ML, Calderón-Montaño JM, Xue X, Luna R, Aguilera A. 2023. DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops. Cell Rep. 42(3):112148.

  43. Pérez D, Moyá ML, Bautista M, León R, Molina-Márquez A, Vila M, Romero-Azogil L, Benito E, de Gracia García-Martín M, Moreno-Gordillo P, Rosado IV, Balestra FR, Huertas P, López-López M, López-Cornejo P. 2023. A novel biocompatible polymer derived from D-mannitol used as a vector in the field of genetic engineering of eukaryotic cells. Colloids Surf B Biointerfaces. 224:113219.

  44. González-Garrido C, Prado F. 2023. Parental histone distribution and location of the replication obstacle at nascent strands control homologous recombination. Cell Rep. 42(3):112174.

  45. Ceppi I, Cannavo E, Bret H, Camarillo R, Vivalda F, Thakur RS, Romero-Franco A, Sartori AA, Huertas P, Guérois R, Cejka P. 2023. PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection. Genes Dev . 37(3-4):119-135.

  46. Bruxel MA, da Silva FN, da Silva RA, Zimath PL, Rojas A, Moreira ELG, Quesada I, Rafacho A. 2023. Preconception exposure to malathion and glucose homeostasis in rats: Effects on dams during pregnancy and post-term periods, and on their progeny. Environ Pollut. 16(Pt 2):120633.