Centro Andaluz de Biología Molecular y Medicina Regenerativa
Selected publications in 2014:

  1. Aguilera A, Gaillard H. 2014. Transcription and recombination: when RNA meets DNA. Cold Spring Harb Perspect Biol. 6(8). pii: a016543.

  2. Alfonso-Pérez T, Domínguez-Sánchez MS, García-Domínguez M, Reyes JC. 2014. Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. Oncogene. doi: 10.1038/onc.2013.276.

  3. Álvarez-Quilón A, Serrano-Benítez A, Lieberman JA, Quintero C, Sánchez-Gutiérrez D, Escudero LM, Cortés-Ledesma F. 2014. ATM specifically mediates repair of double-strand breaks with blocked DNA ends. Nat Commun. 5:3347 .

  4. Berná G, Oliveras-López MJ, Jurado-Ruíz E, Tejedo J, Bedoya F, Soria B, Martín F. 2014. Nutrigenetics and nutrigenomics insights into diabetes etiopathogenesis. Nutrients. 5338-69.

  5. Bhatia V, Barroso SI, García-Rubio ML, Tumini E, Herrera-Moyano E, Aguilera A. 2014. BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2. Nature. 17;511(7509):362-5.

  6. Cruz-García A, López-Saavedra A, Huertas P. 2014. BRCA1 Accelerates CtIP-Mediated DNA-End Resection. Cell Rep. 9(2):451-9.

  7. Delgado I, Carrasco M, Cano E, Carmona R, García-Carbonero R, Marín-Gómez LM, Soria B, Martín F, Cano DA, Muñoz-Chápuli R, Rojas A. 2014. GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice. Hepatology. doi: 10.1002/hep.27005.

  8. Felipe-Abrio I, Lafuente-Barquero J, García-Rubio ML, Aguilera A. 2014. RNA polymerase II contributes to preventing transcription-mediated replication fork stalls. EMBO J. 34(2):236-50.

  9. Gaillard H, Aguilera A. 2014. Cleavage factor I links transcription termination to DNA damage response and genome integrity maintenance in Saccharomyces cerevisiae. PLoS Genet. 10(3):e1004203.

  10. Gálvez P, Clares B, Bermejo M, Hmadcha A, Soria B. 2014. Standard requirement of a microbiological quality control program for the manufacture of human mesenchymal stem cells for clinical use. Stem Cells Dev. 23(10):1074-83.

  11. Garcia-Gutierrez P, Juarez-Vicente F, Wolgemuth DJ, Garcia-Dominguez M. 2014. Pleiotrophin antagonizes Brd2 during neuronal differentiation. J Cell Sci. 127(Pt 11):2554-64.

  12. Herrera-Moyano E, Mergui X, García-Rubio ML, Barroso S, Aguilera A. 2014. The yeast and human FACT chromatin-reorganizing complexes solve R-loop-mediated transcription-replication conflicts. Genes Dev. 28(7):735-48.

  13. Herrera-Moyano E, Moriel-Carretero M, Montelone BA, Aguilera A. 2014. The rem Mutations in the ATP-Binding Groove of the Rad3/XPD Helicase Lead to Xeroderma pigmentosum-Cockayne Syndrome-Like Phenotypes. PLoS Genet. 10(12):e1004859.

  14. Jin S, Kim J, Willert T, Klein-Rodewald T, Garcia-Dominguez M, Mosqueira M, Fink R, Esposito I, Hofbauer LC, Charnay P, Kieslinger M. 2014. Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1. Nat Commun. 5:3793.

  15. Lachaud CC, López-Beas J, Soria B, Hmadcha A. 2014. EGF-induced adipose tissue mesothelial cells undergo functional vascular smooth muscle differentiation. Cell Death Dis. 5:e1304.

  16. Lachaud CC, Soria F, Escacena N, Quesada-Hernández E, Hmadcha A, Alió J, Soria B. 2014. Mesothelial cells: a cellular surrogate for tissue engineering of corneal endothelium. Invest Ophthalmol Vis Sci. 19;55(9):5967-78.

  17. Lukovic D, Moreno-Manzano V, Klabusay M, Stojkovic M, Bhattacharya SS, Erceg S. 2014. Non-coding RNAs in pluripotency and neural differentiation of human pluripotent stem cells. Front Genet. 5:132.

  18. Lukovic D, Stojkovic M, Moreno-Manzano V, Bhattacharya SS, Erceg S. 2014. Perspectives and future directions of human pluripotent stem cell-based therapies: lessons from Geron's clinical trial for spinal cord injury. Stem Cells Dev. 23(1):1-4.

  19. Martín-Pérez R, Palacios C, Yerbes R, Cano-González A, Iglesias-Serret D, Gil J, Reginato MJ, López-Rivas A. 2014. Activated ERBB2/HER2 licenses sensitivity to apoptosis upon endoplasmic reticulum stress through a PERK-dependent pathway. Cancer Res. 74(6):1766-77.

  20. Mora-Castilla S, Tejedo JR, Tapia-Limonchi R, Díaz I, Hitos AB, Cahuana GM, Hmadcha A, Martín F, Soria B, Bedoya FJ. 2014. Transient Downregulation of Nanog and Oct4 Induced by DETA/NO Exposure in Mouse Embryonic Stem Cells Leads to Mesodermal/Endodermal Lineage Differentiation. Stems Cell Int. 2014:379678.

  21. Muñoz-Barrera M, Monje-Casas F. 2014. Increased Aurora B activity causes continuous disruption of kinetochore-microtubule attachments and spindle instability. Proc Natl Acad Sci U S A. 111(38):E3996-4005.

  22. Murillo-Pineda M, Cabello-Lobato MJ, Clemente-Ruiz M, Monje-Casas F, Prado F. 2014. Defective histone supply causes condensin-dependent chromatin alterations, SAC activation and chromosome decatenation impairment. Nucleic Acids Res. pii: gku927.

  23. Prado F. 2014. Genetic instability is prevented by Mrc1-dependent spatio-temporal separation of replicative and repair activities of homologous recombination: homologous recombination tolerates replicative stress by Mrc1-regulated replication and repair activities opera. Bioessays. 36(5):451-62.

  24. Prado, F. 2014. Homologous recombination maintenance of genome integrity during DNA damage tolerance. Molecular & Cellular Oncology. 1, e957039 (2014).

  25. Reyes JC. 2014. The many faces of plant SWI/SNF complex. Mol Plant. 7(3):454-8.

  26. Sánchez-Pérez T, Medema RH, López-Rivas A. 2014. Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL. Oncogene. doi: 10.1038/onc.2013.601.

  27. Santos-Pereira JM, García-Rubio ML, González-Aguilera C, Luna R, Aguilera A. 2014. A genome-wide function of THSC/TREX-2 at active genes prevents transcription-replication collisions. Nucleic Acids Res. pii: gku906.

  28. Santos-Pereira JM, Herrero AB, Moreno S, Aguilera A. 2014. Npl3, a new link between RNA-binding proteins and the maintenance of genome integrity. Cell Cycle. 13(10):1524-9.

  29. Sollier J, Stork CT, García-Rubio ML, Paulsen RD, Aguilera A, Cimprich KA. 2014. Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability. Mol Cell. 56(6):777-85.

  30. Subtil-Rodríguez A, Vázquez-Chávez E, Ceballos-Chávez M, Rodríguez-Paredes M, Martín-Subero JI, Esteller M, Reyes JC. 2014. The chromatin remodeller CHD8 is required for E2F-dependent transcription activation of S-phase genes. Nucleic Acids Res. 42(4):2185-96.

  31. Tapia-Limonchi R, Díaz I, Cahuana GM, Bautista M, Martín F, Soria B, Tejedo JR, Bedoya FJ. 2014. Impact of exposure to low concentrations of nitric oxide on protein profile in murine and human pancreatic islet cells. Islets. 6(5-6):e995997.

  32. Voisset C, García-Rodríguez N, Birkmire A, Blondel M, Wellinger RE. 2014. Using yeast to model calcium-related diseases: Example of the Hailey-Hailey disease. Biochim Biophys Acta. S0167-4889(14)00067-6.