Research Groups
Selected Publications
Nucleic Acids Res EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.
Genes Dev RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.
Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.
Staff
Pablo Huertas
DNA double strand break repair and human disease
Our lab focuses in the understanding on how cells deal with broken chromosomes. Indeed, unbalanced repair of DNA breaks lead to the accumulation of genomic alterations, a phenomenon known as genomic instability that is at the root of the development of several diseases, including cancer and some rare syndromes.
Seminars
The schedule of Cabimer's 2024-2025 seminars will be published in September, but you can see here the list of this year's seminars.
