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eLife. DNA-RNA hybrids at DSBs interfere with repair by homologous recombination.
Nature Communications. Harmful R-loops are prevented via different cell cycle-specific mechanisms.
Nature Communications. Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis.
Nature Communications. ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair.
Nature Communications. CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes.
Anabel Rojas
Organogenesis and diseases of the pancreas and liver
Defects in organogenesis and pancreatic and liver function lead to debilitating diseases such as diabetes and liver cirrhosis. Our group is interested in understanding the molecular and cellular processes through which these organs form during embryonic development and how pancreatic and hepatic cells can regenerate after damage to adult tissue.
- 28 January 2022
Seminario
Ignacio Varela – Use of functional genomics for the study of the role of SWI/SNF in lung cancer - 11 February 2022
Seminario
Rubén López-Vales – Modulation of microglia and macrophage phenotype to mediate repair after central nervous system injury - 18 February 2022
Seminario
Julien Duxin – Mechanisms of DNA crosslink repair
