Centro Andaluz de Biología Molecular y Medicina Regenerativa
News

Please, follow this link to read the news in Spanish.

Selected Publications

eLife. DNA-RNA hybrids at DSBs interfere with repair by homologous recombination.

Nature Communications. Harmful R-loops are prevented via different cell cycle-specific mechanisms.

Nature Communications. Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis.

Nature Communications. ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair.

Nature Communications. CENP-V is required for proper chromosome segregation through interaction with spindle microtubules in mouse oocytes.

Staff

Pablo Huertas

DNA double strand break repair and human disease

Our lab focuses in the understanding on how cells deal with broken chromosomes. Indeed, unbalanced repair of DNA breaks lead to the accumulation of genomic alterations, a phenomenon known as genomic instability that is at the root of the development of several diseases, including cancer and some rare syndromes.

Seminars
The schedule of Cabimer's 2023-2024 seminars will be published in September, but you can see here the list of this year's seminars.

 

Download Conference Series 2022-23