Centro Andaluz de Biología Molecular y Medicina Regenerativa
Selected Publications
Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.
Nat Commun BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis.
Nucleic Acids Res EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.
Nucleic Acids Res Rat1 promotes premature transcription termination at R-loops.
Cell Rep Evolutionary analysis of gene ages across TADs associates chromatin topology with whole-genome duplications.
Staff

Fernando Monje

Cell division control

Advancing in our knowledge about cell division is essential in order to better understand the development of diseases that arise as a consequence of an incorrect regulation of this process, such as cancer. Our group is particularly interested in unveiling the signaling pathways that orchestrate cell cycle progression, as well as in deciphering the molecular mechanisms by which the main cellular checkpoints regulate this process to ensure the fidelity of chromosome segregation.

Seminars
  • 07 June 2024

    Seminario

    Susana Godinho – Microtubules as mediators of stress responses and repair
  • 14 June 2024

    Seminario

    Alfred Vertegaal – Uncovering Small Ubiquitin-like Modifier signal transduction networks in a proteome-wide manner
  • 21 June 2024

    Seminario

    Fernando de Castro – (Re)Myelination:the brain beyond neurons in health and disease

 

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