Centro Andaluz de Biología Molecular y Medicina Regenerativa
Selected Publications
Nucleic Acids Res EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.

Genes Dev RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.

Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.

Clin Transl Med LRH-1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype.

Staff

Fernando Monje

Cell division control

Advancing in our knowledge about cell division is essential in order to better understand the development of diseases that arise as a consequence of an incorrect regulation of this process, such as cancer. Our group is particularly interested in unveiling the signaling pathways that orchestrate cell cycle progression, as well as in deciphering the molecular mechanisms by which the main cellular checkpoints regulate this process to ensure the fidelity of chromosome segregation.

Seminars
  • 17 January 2025

    Seminario

    Juan Méndez – Tolerating DNA damage by repriming: molecular mechanisms and opportunities for cancer therapy
  • 31 January 2025

    Seminario

    Laura Baranello – The regulation of DNA topology by supercoiling, topoisomerases and MYC

Download Conference Series 2023-24