Research Groups
Selected Publications
Nucleic Acids Res EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.
Genes Dev RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.
Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.
Staff
Fernando Monje
Cell division control
Advancing in our knowledge about cell division is essential in order to better understand the development of diseases that arise as a consequence of an incorrect regulation of this process, such as cancer. Our group is particularly interested in unveiling the signaling pathways that orchestrate cell cycle progression, as well as in deciphering the molecular mechanisms by which the main cellular checkpoints regulate this process to ensure the fidelity of chromosome segregation.
Seminars
- 25 October 2024
Seminario
Clara Álvarez – PIAS2b-dsRNAi for Mitotic Catastrophe in Anaplastic Carcinomas - 08 November 2024
Seminario
Darío Lupiáñez – Genomes in 3D: implications for development and evolution
