Research Groups
Selected Publications
Genes Dev RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.
Brain Scn1a haploinsufficiency in the prefrontal cortex engages to cognitive impairment and depressive phenotype.
Clin Transl Med LRH-1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype.
Staff
Fernando Monje
Cell division control
Advancing in our knowledge about cell division is essential in order to better understand the development of diseases that arise as a consequence of an incorrect regulation of this process, such as cancer. Our group is particularly interested in unveiling the signaling pathways that orchestrate cell cycle progression, as well as in deciphering the molecular mechanisms by which the main cellular checkpoints regulate this process to ensure the fidelity of chromosome segregation.
Seminars
- 17 January 2025
Seminario
Juan Méndez – Tolerating DNA damage by repriming: molecular mechanisms and opportunities for cancer therapy - 31 January 2025
Seminario
Laura Baranello – The regulation of DNA topology by supercoiling, topoisomerases and MYC
