Currently I am a Ramon y Cajal Fellow carrying my own, independent research at CABIMER. My work is focused on:
- The identification of the extralysosomal targets of the lysosomal proteases shown to be involved in the regulation of a plethora of physiological processes, such as mitosis, gene expression, or differentiation.
- The characterisation of the role played by cytokines in the regulation of the lysosomal compartment during the immune response.
Furthermore, I have been recently awarded an EMERGIA research grant (Regional Government of Andalusia), starting on September 2023, that will provide further economic support to continue my career as an independent scientist.
During my scientific career I have worked in several scientific projects both at national and international level (European Research Council, Welcome Trust, Medical Research Council, Spanish Ministry of Science), published a number of scientific articles in high-impact factor journals (i.e., Science Immunology, Immunity, Blood, Nature Communications, Nature Structural and Molecular Biology, Cell Reports, eLIFE, among others). I have presented my work at more than 20 national and international conferences, been invited to several talks at international conferences and awarded several fellowships.
During my Postdoctoral work at the University of Dundee (UoD, UK), I led a project about the characterisation of a novel STAT3-mediated pathway of lysosomal homeostasis in which I designed and executed all the experiments, leading to a first and corresponding author paper in Nature Communications in 2018. This allowed me to secure a position as Senior Research Associate (SRA) at the UoD in which I developed my own, independent line of research. Importantly, my stay in the United Kingdom has allowed me to stablish collaborations with some of the world leading experts in the fields of Immunology (Prof. Colin Watts (UK); Prof. Doreen Cantrell (UK), Dr Suman Mitra (FR)), Lysosomal Biology (Prof. Thomas Reinheckel (DE); Prof. Valeria Poli (IT)), Bioinformatics (Prof. Angus Lamond (UK); Dr Majid Kazemian (USA)) and Cytokine Biology (Dr Ignacio Moraga (UK)). This excellent network of collaborators provides excellent support in the development of my scientific career, allowing me to explore lysosomal biology from different scientific perspectives.
I have co-supervised three TFM students (two during my stay in the UK and one back in Spain). Currently, I am supervising two TFG students at the USE. This, combined with my scientific accolades, further confirms my leadership and scientific independence. I have recently become a member of the Scientific Advisory Board of the Spanish Research Agency and I am part of the Editorial Advisory Board of FEBS Open BIO, peer-reviewed manuscripts for several journals (FEBS Open BIO, Journal of Plant Research, Frontiers in Immunology, Journal of Clinical Medicine, etc), been a member of the organising committee of several international scientific meetings and been invited to several talks. I have recently served as editor guest for a special issue of FEBS Open BIO focused on lysosomes. During my scientific career I have been directly involved in the organisation of outreach activities. From 2008 to 2010, during my PhD studies, I participated in the “Science Fair” event organised by the US-CSIC. From 2015 to 2019, during my stay in the UK, I was involved in the organisation of the “Incredible Immunology” event.
- MSCA fellow at Prof. Irene Diaz-Moreno’s lab, cicCartuja, Seville, Spain (2021-2022)
- Senior Research Associate at Dr. Ignacio Moraga’s lab, Life Sciences Institute, University of Dundee, UK (2017-2021)
- Postdoctoral research associate at Prof. Colin Watts’ lab, Life Sciences Institute, University of Dundee, UK (2012-2017)
- PhD student at Prof. Miguel A De la Rosa’s lab, cicCartuja, Seville, Spain (2007-2011)