Centro Andaluz de Biología Molecular y Medicina Regenerativa
Selected publications in 2019:

  1. Ariza L, Rojas A, Muñoz-Cápuli R, Carmona R. 2019. The Wilms' tumor suppressor gene regulates pancreas homeostasis and repair. Plos Genetics. 15(2):e1007971.

  2. Barroso S, Herrera-Moyano E, Muñoz S, García-Rubio M, Gómez-González B, Aguilera A. 2019. The DNA damage response acts as a safeguard against harmful DNA-RNA hybrids of different origins. EMBO reports. 20(9):e47250.

  3. Bru-Tari E, Cobo-Vuilleumier N, Alonso-Magdalena P, Dos Santos RS, Marroqui L, Nadal A, Gauthier BR, Quesada I. 2019. Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes. Sci Rep. 9(1):9515.

  4. Caro C, Quaresma P, Pereira E, Franco J, Pernia Leal M, García-Martín ML, Royo JL, Oliva-Montero JM, Merkling PJ, Zaderenko AP, Pozo D, Franco R. 2019. Synthesis and Characterization of Elongated-Shaped Silver Nanoparticles as a Biocompatible Anisotropic SERS Probe for Intracellular Imaging: Theoretical Modeling and Experimental Verification. Nanomaterials (Basel. 9(2). pii: E256.

  5. Cobo-Vuilleumier N, Lorenzo PI, Gauthier BR. 2019. Targeting LRH-1/NR5A2 to treat type 1 diabetes mellitus. Cell Stress. 2(6):141-143.

  6. de la Cerda B, Díez-Lloret A, Ponte B, Vallés-Saiz L, Calado SM, Rodríguez-Bocanegra E, Garcia-Delgado AB, Moya-Molina M, Bhattacharya SS, Díaz-Corrales FJ. 2019. Generation and characterization of the human iPSC line CABi001-A from a patient with retinitis pigmentosa caused by a novel mutation in PRPF31 gene. Stem Cell Res. 36:101426.

  7. Domingo-Prim J, Endara-Coll M, Bonath F, Jimeno S, Prados-Carvajal R, Friedländer MR, Huertas P, Visa N. 2019. EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks. Nat Communication. 10(1):2135.

  8. Falcón D, Galeano-Otero I, Calderón-Sánchez E, Del Toro R, Martín-Bórnez M, Rosado JA, Hmadcha A, Smani T. 2019. TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling. Front Physiol. 10:159.

  9. Fuente-Martín E, Mellado-Gil JM, Cobo-Vuilleumier N, Martín-Montalvo A, Romero-Zerbo SY, Diaz Contreras I, Hmadcha A, Soria B, Martin Bermudo F, Reyes JC, Bermúdez-Silva FJ, Lorenzo PI, Gauthier BR. 2019. Dissecting the Brain/Islet Axis in Metabesity. Genes (Basel). 10(5). pii: E350.

  10. Gaillard H, Santos-Pereira JM, Aguilera A. 2019. The Nup84 complex coordinates the DNA damage response to warrant genome integrity. Nucleic Acids Res. 47(8):4054-4067.

  11. Gallego-Durán R, Álvarez-Amor L, Gil-Gómez A, Rojas Á, Muñoz-Hernández R, Cádernas-García A, Maya-Miles D, Montero-Vallejo R, Gato S, Sánchez Torrijos Y, Ampuero J, Martín F, Romero-Gómez M. 2019. Metabolic characterization of two different non-alcoholic fatty liver disease pre-clinical mouse models. Rev Esp Enferm Dig. 111(4):301-307.

  12. García Delgado AB, de la Cerda B, Alba Amador J, Valdés Sánchez ML, Fernández-Muñoz B, Relimpio López I, Rodríguez de la Rúa E, Díez Lloret A, Calado SM, Sánchez Pernaute R, Bhattacharya SS, Díaz Corrales FJ. 2019. Subretinal transplant of iPSC-derived retinal pigment epithelium on nanostructured fibrin-agarose. Tissue Eng Part A. 25(9-10).

  13. Garcia-Delgado AB, Calado SM, Valdes-Sanchez LM, Montero-Sanchez A, Ponte-Zuñiga B, de la Cerda B, Bhattacharya SS, Diaz-Corrales FJ. 2019. Generation of a human iPS cell line (CABi003-A) from a patient with age-related macular degeneration carrying the CFH Y402H polymorphism. Stem Cell Res. 38:101473 .

  14. Garcia-Muse T, Galindo-Diaz U, Garcia-Rubio M, Martin JS, Polanowska J, O'Reilly N, Aguilera A, Boulton SJ. 2019. A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs. Cell Rep. 26(3):775-787.

  15. García-Rodríguez N, Ulrich Hellen D. 2019. A dual system to manipulate protein levels for DNA replication-and cell cycle related studies. Methods in Enzymology. 619:121-143.

  16. Gauthier BR, Bermúdez-Silva FJ. 2019. Advances in Genetics of Regeneration in Metabesity. Genes (Basel). 10(5). pii: E383.

  17. Gómez-González B, Aguilera A. 2019. Transcription-mediated replication hindrance: a major driver of genome instability. Genes Dev. 33(15-16).

  18. Jachimowicz RD, Beleggia F, Isensee J, Velpula BB, Goergens J, Bustos MA, Doll MA, Shenoy A, Checa-Rodriguez C, Wiederstein JL, Baranes-Bachar K, Bartenhagen C, Hertwig F, Teper N, Nishi T, Schmitt A, Distelmaier F, Lüdecke HJ, Albrecht B, Krüger M, Schumacher B, Geiger T, Hoon DSB, Huertas P, Fischer M, Hucho T, Peifer M, Ziv Y, Reinhardt HC, Wieczorek D, Shiloh Y. 2019. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 176(3):505-519.

  19. Jimeno S, Mejías-Navarro F, Prados-Carvajal R, Huertas P. 2019. Controlling the balance between chromosome break repair pathways. Adv Protein Chem Struct Biol. 115:95-134.

  20. Jimeno S, Prados-Carvajal R, Huertas P. 2019. The role of RNA and RNA-related proteins in the regulation of DNA double strand break repair pathway choice. DNA Repair (Amst). 81:102662.

  21. Jurado-Ruiz E, Álvarez-Amor L, Varela LM, Berná G, Parra-Camacho MS, Oliveras-Lopez MJ, Martínez-Force E, Rojas A, Hmadcha A, Soria B, Martín F. 2019. Extra virgin olive oil diet intervention improves insulin resistance and islet performance in diet-induced diabetes in mice. Sci Rep. 9(1):11311.

  22. López-Noriega L, Capilla-González V, Cobo-Vuilleumier N, Martin-Vazquez E, Lorenzo PI, Martinez-Force E, Soriano-Navarro M, García-Fernández M, Romero-Zerbo SY, Bermúdez-Silva FJ, Díaz-Contreras I, Sánchez-Cuesta A, Santos-Ocaña C, Hmadcha A, Soria B, Martín F, Gauthier BR, Martin-Montalvo A. 2019. Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging. Aging (Albany NY). 11(18):7746-7779.

  23. Luna-Peláez N, March-Díaz R, Ceballos-Chávez M, Guerrero-Martínez JA, Grazioli P, García-Gutiérrez P, Vaccari T, Massa V, Reyes JC, García-Domínguez M. 2019. The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes. Cell Death Dis. 10(8):548.

  24. Mannini B, Vecchi G, Labrador-Garrido A, Fabre B, Fani G, Franco JM, Lilley K, Pozo D, Vendruscolo M, Chiti F, Dobson CM, Roodveldt C. 2019. Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers. ACS Chem Neurosci. 10(8):3464-3478.

  25. Manzano-López J, Matellán L, Álvarez-Llamas A, Blanco-Mira JC, Monje-Casas F. 2019. Asymmetric inheritance of spindle microtubule-organizing centres preserves replicative lifespan. Nature Cell Biology. 21(8):952-965.

  26. Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD. 2019. NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPAR? activity. J Gerontol A Biol Sci Med Sci. Epub ahead of print.

  27. Marín-Aguilar F, Castejón-Vega B, Alcocer-Gómez E, Lendines-Cordero D, Cooper MA, de la Cruz P, Andújar-Pulido E, Pérez-Alegre M, Muntané J, Pérez-Pulido AJ, Ryffel B, Robertson AAB, Ruiz-Cabello J, Bullón P, Cordero MD. 2019. NLRP3 inflammasome inhibition by MCC950 in aged mice improves health via enhanced autophagy and PPAR activity. J Gerontol A Biol Sci Med Sci. Epub ahead of print.

  28. Martin-Montalvo A, López-Noriega L, Jiménez-Moreno C, Herranz A, Lorenzo PI, Cobo-Vuilleumier N, Tamayo A, González-Guerrero C, Hofsteede JSWR, Lebreton F, Bosco D, Toscano MG, Herranz L, Anselmo J, Moreno JC, Gauthier BR. 2019. Transient PAX8 Expression in Islets During Pregnancy Correlates With Beta Cell Survival Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus. Diabetes. Epub ahead of print.

  29. Martinez-Pinna J, Marroqui L, Hmadcha A, Lopez-Beas J, Soriano S, Villar-Pazos S, Alonso-Magdalena P, Dos Santos RS, Quesada I, Martin F, Soria B, Gustafsson JÅ, Nadal A. 2019. Oestrogen receptor beta mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells. Diabetologia. 62(9):1667-1680.

  30. Maya-Miles D, Andújar E, Pérez-Alegre M, Murillo-Pineda M, Barrientos-Moreno M, Cabello-Lobato MJ, Gómez-Marín E, Morillo-Huesca M, Prado F. 2019. Crosstalk between chromatin structure, cohesin activity and transcription. Epigenetics Chromatin. 12(1):47.

  31. Merle BMJ, Colijn JM, Cougnard-Grégoire A, de Koning-Backus APM, Delyfer MN, Kiefte-de Jong JC, Meester-Smoor M, Féart C, Verzijden T, Samieri C, Franco OH, Korobelnik JF, Klaver CCW, Delcourt C; EYE-RISK Consortium. 2019. Mediterranean Diet and Incidence of Advanced Age-Related Macular Degeneration: The EYE-RISK Consortium. OPHTALMOLOGY. 126(3):381-390.

  32. Miguel Cabello, Marta Mozo, Berta De la Cerda, Carmen Aracil, Francisco J Diaz-Corrales, Francisco Perdigones, Lourdes Valdes-Sanchez, Isabel Relimpio, Shom S Bhattacharya, Jose Manuel Quero. 2019. Electrostimulation in an autonomous culture lab-on-chip provides neuroprotection of a retinal explant from a retinitis pigmentosa mouse-model. Sensors and Actuators B: Chemical. j.snb.2019.02.118.

  33. Morillo-Huesca M, Murillo-Pineda M, Barrientos-Moreno M, Gómez-Marín E, Clemente-Ruiz M, Prado F. 2019. Actin and Nuclear Envelope Components Influence Ectopic Recombination in the Absence of Swr1. Genetics. Epub ahead of print.

  34. Pintado-Berninches L, Fernandez-Varas B, Benitez-Buelga C, Manguan-Garcia C, Serrano-Benitez A, Iarriccio L, Carrillo J, Guenechea G, Egusquiaguirre SP, Pedraz JL, Hernández RM, Igartua M, Arias-Salgado EG, Cortés-Ledesma F, Sastre L, Perona R. 2019. GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells. Cell Death Diffe. 26(10):1998-2014.

  35. Rivero S, Gómez-Marín E, Guerrero-Martínez JA, García-Martínez J, Reyes JC. 2019. TBL1 is required for the mesenchymal phenotype of transformed breast cancer cells. Cell Death Dis. 10(2): 95.

  36. Rondón AG, Aguilera A. 2019. What causes an RNA-DNA hybrid to compromise genome integrity?. DNA Repair (Amst). 81:102660.

  37. Salas-Armenteros I, Barroso SI, Rondón AG, Pérez M, Andújar E, Luna R, Aguilera A. 2019. Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability. Cell Report. 28(6):1551-1563.

  38. Serrano-Saenz S, Palacios C, Delgado-Bellido D, López-Jiménez L, Garcia-Diaz A, Soto-Serrano Y, Casal JI, Bartolomé RA, Fernández-Luna JL, López-Rivas A, Oliver FJ. 2019. PIM kinases mediate resistance of glioblastoma cells to TRAIL by a p62/SQSTM1-dependent mechanism. Cell Death Dis. 10(2):51.

  39. Soria B, Martin-Montalvo A, Aguilera Y, Mellado-Damas N, López-Beas J, Herrera-Herrera I, López E, Barcia JA, Alvarez-Dolado M, Hmadcha A, Capilla-González V. 2019. Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy. Front Cell Neuroscience. 13:204. doi: 10.3389/fnce.

  40. Soria-Juan B, Escacena N, Capilla-González V, Aguilera Y, Llanos L, Tejedo JR, Bedoya FJ, Juan V, De la Cuesta A, Ruiz-Salmerón R, Andreu E, Grochowicz L, Prósper F, Sánchez-Guijo F, Lozano FS, Miralles M, Del Río-Solá L, Castellanos G, Moraleda JM, Sackstein R, García-Arranz M, García-Olmo D, Martín F, Hmadcha A, Soria B. 2019. Cost-Effective, Safe, and Personalized Cell Therapy for Critical Limb Ischemia in Type 2 Diabetes Mellitus. Front Immunol. 10:1151.

  41. Tisch N, Freire-Valls A, Yerbes R, Paredes I, La Porta S, Wang X, Martín-Pérez R, Castro L, Wong WW, Coultas L, Strilic B, Gröne HJ, Hielscher T, Mogler C, Adams R, Heiduschka P, Claesson-Welsh L, Mazzone M, López-Rivas A, Schmidt T, Augustin HG, Ruiz de Almodovar C. 2019. Caspase-8 modulates physiological and pathological angiogenesis during retina development. J Clin Invest. Epub ahead of print.

  42. Tumini E, Herrera-Moyano E, San Martín-Alonso M, Barroso S, Galmarini CM, Aguilera A. 2019. The Antitumor Drugs Trabectedin and Lurbinectedin Induce Transcription-Dependent Replication Stress and Genome Instability. Mol Canc Research. 17(3):773-782.

  43. Vakilian M, Tahamtani Y, Ghaedi K. 2019. A review on insulin trafficking and exocytosis. Gene. Epub ahead of print.

  44. Villamayor L, Cano DA, Rojas A. 2019. GATA factors in pancreas development and disease. IUBMB Life. Epub ahead of print .

  45. Zatreanu D, Han Z, Mitter R, Tumini E, Williams H, Gregersen L, Dirac-Svejstrup AB, Roma S, Stewart A, Aguilera A, Svejstrup JQ. 2019. Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability. Mol Cell. 76(1):57-69.e9.

  46. Zoeisha S Chinoy,  Clément Bodineau, CamiLLE Favre, Kelley W Moremen, Raúl V Durán, Frédéric Friscourt. 2019. Selective Engineering of Linkage Specific ?2,6?N?Linked Sialoproteins using Sydnone?Modified Sialic Acid Bioorthogonal Reporters. Angewandte Chemie International Edition. 58(13):4281-4285.

  47. Zucchetti AE, Bataille L, Carpier JM, Dogniaux S, San Roman-Jouve M, Maurin M, Stuck MW, Rios RM, Baldari CT, Pazour GJ, Hivroz C. 2019. Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse. Nat Communication. 10(1):2864.