Nat Commun. LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Neuron. Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer’s Disease.
Diabetes. GATA6 Controls Insulin Biosynthesis and Secretion in Adult ß cell.
Glia. Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.
PLoS Genet. The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage.
Ralf Erik Wellinger
Mitochondrial Plasticity and Replication
The genetic material including mitochondrial, telomeric and nucleolar (ribosomal) DNA is constantly exposed to endogenous or exogenous stress. We are particularly interested in the factors and molecular pathways causing genome instability, disease and premature aging.
- 01 June 2018
SeminarioMiguel López – Is brain AMPK a realistic target against obesity?
- 08 June 2018
SeminarioMiriam Cnop – Endoplasmic reticulum stress: the Achilles heel of pancreatic beta cells
- 15 June 2018
SeminarioManuel R. Benito de las Heras – Autophagy as protective mechanism of pancreatic beta cells survival: The aggression of amylin