Research Groups
Core Facilities
Selected Publications
Diabetes. Transient PAX8 Expression in Islets During Pregnancy Correlates With Beta Cell Survival Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus.
PNAS. Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability.
Cell Reports. The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures.
Mol. Ther. PDGF restores the defective phenotype of adipose-derived mesenchymal stromal cells from diabetic patients.
EMBO Rep. The dual role of the centrosome in organizing the microtubule network in interphase.
Staff
David Pozo Perez
Cellular and Molecular Neuroimmunology
Not so long ago, immune responses in neurodegeneration were regarded as rare birds in the field of clinical neurology. Today, they are increasingly moving toward centre stage. The rationale behind includes the recognition that most of the relevant immune molecules are produced within the brain, that microglia among other immune-competent cells are proficient tools shaping neuronal circuitry and fate, and that systemic immune responses affect brain function in health and disease. Our group is interested in how the immune system inside the central nervous system is finely regulated at molecular and cellular levels. We are focused on the role of neuro-immune interactions in Parkinson’s disease (PD) and Amyotrophic Lateral Sclerosis (ALS).
Seminars
- 18 January 2019
Seminario
Roger Gomis – Tissue-specific and time-dependent mechanisms of metastasis - 01 February 2019
Seminario
Claudio de Virgilio – Regulation of TORC1 by Amino Acids: a Central Role for Rag GTPases Within the EGO Complex - 06 February 2019
Seminario
José Ignacio Martí-Subero – Reference epigenomes and 3D genomes in normal and neoplastic B cells - 08 February 2019
Seminario
Thanos Halazonetis -DNA replication stress and cancer
