PNAS. Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability.
EMBO J. Human THO-Sin3A interaction reveals new mechanisms to prevent R-loops that cause genome instability.
Curr Biol. Late rDNA Condensation Ensures Timely Cdc14 Release and Coordination of Mitotic Exit Signaling with Nucleolar Segregation.
Organogenesis and diseases of the pancreas and liver
Defects in organogenesis and pancreatic and liver function lead to debilitating diseases such as diabetes and liver cirrhosis. Our group is interested in understanding the molecular and cellular processes through which these organs form during embryonic development and how pancreatic and hepatic cells can regenerate after damage to adult tissue.
- 19 January 2018
SeminarioXosé J. Bustelo – Role of Vav oncoproteins in cancer: from mice to humans and viceversa
- 26 January 2018
SeminarioJuan M. Vaquerizas – Chromatin architecture in development and disease