The EMBO Journal. BRCA2 promotes R‐loop resolution by DDX5 helicase at DNA breaks to facilitate their repair by homologous recombination.
eLife. TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin.
Nature Communications. TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains.
eLife. Polo-like kinase acts as a molecular timer that safeguards the asymmetric fate of spindle microtubule-organizing centers.
eLife. Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independet manner.
Cell division control
Advancing in our knowledge about cell division is essential in order to better understand the development of diseases that arise as a consequence of an incorrect regulation of this process, such as cancer. Our group is particularly interested in unveiling the signaling pathways that orchestrate cell cycle progression, as well as in deciphering the molecular mechanisms by which the main cellular checkpoints regulate this process to ensure the fidelity of chromosome segregation.
- 12 March 2021
SeminarioRicardo Pardal – Physiology of the adult carotid body germinal niche
- 09 April 2021
SeminarioPlácido Navas – Pathogenic mechanisms of CoQ deficiency
- 14 May 2021
SeminarioMaría García Parajo – Unraveling the dynamic nano- and meso-scale architecture of the living cell membrane