Selected Publications
Surv Ophthalmol Pharmacological agents for treatment of proliferative vitreoretinopathy: A systematic review and network meta-analysis.
Science advances HMCES corrupts replication fork stability during base excision repair in homologous recombination-deficient cells.
Proc Natl Acad Sci U S A Patulin and Xestoquinol are inhibitors of DNA topoisomerase 1.
Staff
Tatiana García Muse
DNA damage response during meiosis
Genomic DNA is under constant attack from both endogenous and exogenous DNA damaging agents. Without proper repair the resulting DNA damages would lead to alteration of genomic structure thus affecting the faithful transmission of genetic information. In addition, defects during meiosis lead to aneuploidy, an extreme kind of genetic instability associated with fertility problems, miscarriages and mental retardation syndromes. I use the Caenorhabditis elegans model organism to address the impact of DNA damage on genome stability in meiotic cells.
Seminars
- 14 November 2025
Seminario
Simón Méndez Ferre – Harnessing the microenvironmental regulation for improved treatment of myeloid malignancies - 21 November 2025
Seminario
Ana Viñuela – Using direct long-read RNA sequencing to solve the variant-to-function problem
