Centro Andaluz de Biología Molecular y Medicina Regenerativa
Selected Publications
Cell Rep Evolutionary analysis of gene ages across TADs associates chromatin topology with whole-genome duplications.
Cell Rep SWI/SNF-dependent genes are defined by their chromatin landscape.
Nucleic Acids Res Rat1 promotes premature transcription termination at R-loops.
Blood Cancer J PICH deficiency limits the progression of MYC-induced B-cell lymphoma.
Cell Metab H2S serves as the immunoregulatory essence of apoptotic cell death.
Staff

Tatiana García Muse

DNA damage response during meiosis

Genomic DNA is under constant attack from both endogenous and exogenous DNA damaging agents. Without proper repair the resulting DNA damages would lead to alteration of genomic structure thus affecting the faithful transmission of genetic information. In addition, defects during meiosis lead to aneuploidy, an extreme kind of genetic instability associated with fertility problems, miscarriages and mental retardation syndromes. I use the Caenorhabditis elegans model organism to address the impact of DNA damage on genome stability in meiotic cells.

Seminars
The schedule of Cabimer's 2024-2025 seminars will be published in September, but you can see here the list of this year's seminars.

 

Download Conference Series 2023-24