Prof. M. Pia Cosma
Centre de Regulació Genòmica (CRG), Barcelona, Spain
Dissecting mechanisms controlling somatic cell reprogramming and tissue regeneration
Spontaneous cell fusion between two cells of different lineages can originate new hybrid cells that have different features from the original parent cells. Activation of the Wnt/B-catenin signalling pathway enhances reprogramming of somatic cells after their fusion with embryonic stem cells. We are dissecting the gene networks and studying the mechanisms of in-vivo somatic cell reprogramming, to determine whether reprogrammed hybrids have the potential to differentiate and regenerate tissues.
Cabimer, Salón de actos
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